Clinical research arising from collaborations of members of the SAYA U.S. National Consortium
2026
Prevention and Treatment of Maternal Stroke in Pregnancy and Postpartum: A Scientific Statement From the American Heart Association
Elliza Miller leads a multidisciplinary group of experts including Michelle Leppert and Katelyn Skeels to set the stage for prevention and treatment of maternal stroke in this AHA-ASA Scientific Statement.
Sex Differences in Young Adult Stroke Severity Using Linked Colorado-All Payer’s Claims Database and the Get With The Guidelines-Stroke Registry
Michelle Leppert, Eliza Miller, and Sharon Poisson explore sex differences in the severity of young adults with stroke through a novel linkage of the Colorado-All Payer’s Claims Database and the AHA-ASA Get with the Guidelines quality registry, finding similar severity of ischemic stroke between women and men.
2024
Building Centers of Excellence for the Care of Young Adults With Stroke
Lester Leung, Sarah Lee, and Aneesh Singhal of the SAYA U.S. National Consortium lay out a vision for the advancement of young stroke care in the U.S. through the building of centers of excellence. Click the link below to read more about best practices and optimal infrastructure to support young people with stroke.
Association of Traditional and Nontraditional Risk Factors in the Development of Strokes Among Young Adults by Sex and Age Group: A Retrospective Case-Control Study
Michelle Leppert and Sharon Poisson determine that nontraditional risk factors are just as important for young adults with stroke as traditional risk factors, with stronger associations in young adults under age 35.
2022
Detection of symptoms of late complications after stroke in young survivors with active surveillance versus usual care
Lester Leung and David Thaler of the Tufts SAYA Program assess rates of detection of late complications after stroke in a young stroke clinic using active surveillance with a questionnaire vs routine care.
Systematic Review of Sex Differences in Ischemic Strokes Among Young Adults: Are Young Women Disproportionately at Risk?
Michelle Leppert and Sharon Poisson lead a systematic review to assess differences in risk of ischemic stroke among women and men, finding that women are at greater risk for ischemic stroke at 35 years of age and younger.
Black-white Differences in Left Ventricular Hypertrophy Rates Among Young Adults with Ischemic Stroke
Carolyn Cronin and Michael Phipps team up with the Stroke Prevention in Young Adults Study to explore differences in left ventricular hypertrophy among white and black young adults with ischemic stroke.
Differences in Multiple Risk Factors Between Black and White Individuals With Young-Onset Ischemic Stroke
Carolyn Cronin and Michael Phipps explore multiple risk factors among young adults with ischemic stroke, finding that young black people with stroke are much more likely to have multiple risk factors.
Black-White Differences in Ischemic Stroke Risk Factor Burden in Young Adults
Carolyn Cronin and Michael Phipps study differences in risk factors in the Baltimore-DC area. They found that hypertension is the strongest contributor to stroke among young black people, and tobacco use is the strongest contributor to stroke among young white people.
2020
Young Women Had More Strokes Than Young Men
in a Large, United States Claims Sample
Michelle Leppert and Sharon Poisson assess rates of stroke among young women and men in the large PharMetrics nationally representative claims database.
Differences in presenting symptoms of acute stroke among young and older adults
Lester Leung and David Thaler compare presenting symptoms of acute stroke in young and older adults, finding that younger adults are more likely to experience progression or fluctuation of stroke deficits in the first 24 hours as compared to older adults.
2017
Longitudinal Care for Young Adults With Stroke
Lester Leung, Emiliya Melkumova, and David Thaler describe the value of longitudinal care for young adults with stroke, including identification and management of late complications after stroke and survivorship support.
Cryptogenic Stroke and Patent Foramen Ovale Risk Assessment
David Thaler and Emiliya Melkumova describe PFO risk assessment among patients with cryptogenic ischemic stroke.